Berberine, los yog berberine hydrochloride, yog ib qho chaw muaj nyob hauv ntau cov nroj tsuag. Nws tuaj yeem pab kho cov mob xws li ntshav qab zib, cov roj (cholesterol) siab thiab ntshav siab. Txawm li cas los xij, cov kev mob tshwm sim tuaj yeem muaj xws li mob plab thiab xeev siab.
Berberine yog ib feem ntawm cov tshuaj suav tshuaj suav thiab Ayurvedic rau ntau txhiab xyoo. Nws ua rau lub cev sib txawv thiab muaj peev xwm ua rau muaj kev hloov pauv hauv cov hlwb ntawm lub cev.
Kev tshawb fawb ntawm berberine qhia tias nws tuaj yeem kho ntau yam kab mob metabolic, suav nrog ntshav qab zib, rog, thiab kab mob plawv. Nws kuj tseem tuaj yeem txhim kho plab hnyuv.
Txawm hais tias berberine zoo li muaj kev nyab xeeb thiab muaj kev phiv tsawg, koj yuav tsum sab laj nrog koj tus kws kho mob ua ntej noj nws.
Berberine tej zaum yuav yog ib qho tshuaj tua kab mob zoo. Ib txoj kev tshawb fawb 2022 pom tias berberine pab inhibit qhov kev loj hlob ntawm Staphylococcus aureus.
Lwm txoj kev tshawb nrhiav pom tias berberine tuaj yeem ua rau cov DNA thiab cov proteins ntawm qee cov kab mob.
Kev tshawb fawb qhia tau hais tias berberine muaj cov tshuaj tiv thaiv kab mob, txhais tau tias nws tuaj yeem pab kho mob ntshav qab zib thiab lwm yam kab mob cuam tshuam nrog o.
Kev tshawb fawb qhia tias berberine tuaj yeem ua tau zoo hauv kev kho mob ntshav qab zib. Kev tshawb fawb tau pom tias nws tuaj yeem muaj txiaj ntsig zoo rau:
Tib qhov kev tshuaj xyuas pom tau tias kev sib xyaw ntawm berberine thiab cov tshuaj txo cov ntshav qab zib tau zoo dua li cov tshuaj ib leeg.
Raws li kev tshawb fawb xyoo 2014, berberine qhia tau hais tias muaj peev xwm kho mob ntshav qab zib mellitus, tshwj xeeb tshaj yog rau cov neeg uas tsis tuaj yeem noj cov tshuaj tiv thaiv kab mob uas twb muaj lawm vim muaj kab mob plawv, mob siab, lossis teeb meem raum.
Lwm qhov kev tshuaj xyuas ntawm cov ntaub ntawv pom tau tias berberine ua ke nrog kev ua neej hloov pauv txo cov ntshav qab zib ntau dua li kev hloov pauv hauv kev ua neej ib leeg.
Berberine zoo li ua kom AMP-activated protein kinase, uas pab tswj lub cev siv cov ntshav qab zib. Cov kws tshawb fawb ntseeg tias qhov kev ua haujlwm no tuaj yeem pab kho mob ntshav qab zib thiab cov teeb meem kev noj qab haus huv xws li rog rog thiab cov roj cholesterol siab.
Lwm xyoo 2020 meta-kev soj ntsuam pom kev txhim kho hauv lub cev qhov hnyav thiab cov kab mob metabolic yam tsis muaj qhov nce ntxiv hauv daim siab enzyme.
Txawm li cas los xij, cov kws tshawb fawb yuav tsum ua cov kev tshawb fawb loj dua, ob qhov muag tsis pom kev los txiav txim siab txog kev nyab xeeb thiab kev ua tau zoo ntawm berberine.
Tham nrog koj tus kws kho mob ua ntej noj berberine rau ntshav qab zib. Tej zaum nws yuav tsis haum rau txhua tus thiab tej zaum yuav cuam tshuam nrog lwm cov tshuaj.
Cov roj (cholesterol) siab thiab qis lipoprotein tsawg (LDL) triglycerides tuaj yeem ua rau muaj kab mob plawv thiab mob stroke.
Qee cov pov thawj qhia tias berberine tuaj yeem pab txo qis LDL cholesterol thiab triglycerides. Raws li ib qho kev txheeb xyuas, tsiaj txhu thiab tib neeg kev tshawb fawb qhia tias berberine txo cov roj cholesterol.
Qhov no tuaj yeem pab txo qis LDL, "phem" cholesterol, thiab nce HDL, "zoo" cholesterol.
Kev tshuaj xyuas ntawm cov ntaub ntawv pom tau tias berberine ua ke nrog kev hloov hauv kev ua neej yog qhov zoo dua rau kev kho cov roj cholesterol ntau dua li kev hloov pauv hauv kev ua neej ib leeg.
Cov kws tshawb fawb ntseeg tias berberine tuaj yeem ua zoo ib yam li cov tshuaj txo cov roj cholesterol yam tsis ua rau muaj kev phiv tib yam.
Kev tshuaj xyuas ntawm cov ntaub ntawv pom tau tias berberine muaj txiaj ntsig zoo hauv kev sib xyaw nrog cov tshuaj txo cov ntshav siab dua li ntawm nws tus kheej.
Tsis tas li ntawd, cov txiaj ntsig tau los ntawm cov kev tshawb fawb nas qhia tias berberine tuaj yeem ncua qhov pib ntawm cov ntshav siab thiab pab txo qis nws qhov hnyav thaum ntshav siab tshwm sim.
Ib qho kev ntsuam xyuas tau tshaj tawm qhov hnyav hnyav hauv cov neeg noj 750 milligrams (mg) ntawm barberry ob zaug ib hnub rau 3 lub hlis. Barberry yog ib tsob nroj uas muaj ntau ntawm berberine.
Tsis tas li ntawd, ib txoj kev tshawb nrhiav ob qhov muag tsis pom pom tias cov neeg uas muaj cov kab mob metabolic uas tau noj 200 mg ntawm barberry peb zaug ib hnub twg muaj qhov qis dua lub cev qhov hnyav.
Ib pab neeg ua lwm txoj kev tshawb fawb tau sau tseg tias berberine tuaj yeem ua rau cov nqaij adipose xim av. Cov ntaub so ntswg no pab lub cev hloov cov zaub mov rau hauv lub cev kub, thiab kev ua kom muaj zog tuaj yeem pab kho kev rog thiab metabolic syndrome.
Qee qhov kev tshawb fawb qhia tias berberine ua haujlwm zoo ib yam li cov tshuaj metformin, uas cov kws kho mob feem ntau sau tshuaj kho mob ntshav qab zib hom 2. Qhov tseeb, berberine tuaj yeem muaj peev xwm hloov cov kab mob hauv plab, uas tuaj yeem pab kho kev rog thiab ntshav qab zib.
Polycystic zes qe menyuam syndrome (PCOS) tshwm sim thaum cov poj niam muaj qib siab ntawm qee cov txiv neej cov tshuaj hormones. Lub syndrome yog ib qho hormonal thiab metabolic tsis txaus uas tuaj yeem ua rau muaj menyuam tsis taus thiab lwm yam teebmeem kev noj qab haus huv.
Polycystic ovary syndrome yog txuam nrog ntau yam teeb meem uas berberine tuaj yeem pab daws tau. Piv txwv li, cov neeg muaj PCOS kuj tseem muaj:
Cov kws kho mob qee zaum sau tshuaj metformin, tshuaj kho mob ntshav qab zib, los kho PCOS. Txij li thaum berberine muaj cov txiaj ntsig zoo sib xws rau metformin, nws kuj tseem yog qhov kev kho mob zoo rau PCOS.
Kev tshuaj xyuas zoo pom berberine tau cog lus rau kev kho mob polycystic zes qe menyuam nrog insulin tsis kam. Txawm li cas los xij, cov kws sau ntawv sau tseg tias kev lees paub ntawm cov teebmeem no yuav tsum tau tshawb fawb ntxiv.
Berberine tuaj yeem ua rau muaj kev hloov pauv hauv cellular molecules, uas tuaj yeem muaj lwm yam txiaj ntsig zoo: tiv thaiv qog noj ntshav.
Lwm txoj kev tshawb fawb qhia tias berberine pab kho mob qog noj ntshav los ntawm inhibiting nws txoj kev loj hlob thiab lub neej voj voog. Nws kuj tseem tuaj yeem ua lub luag haujlwm hauv kev tua cov qog nqaij hlav cancer.
Raws li cov ntaub ntawv no, cov kws sau ntawv hais tias berberine yog "zoo heev, nyab xeeb, thiab pheej yig" tshuaj tiv thaiv kab mob.
Txawm li cas los xij, nws yog ib qho tseem ceeb uas yuav tsum nco ntsoov tias cov kws tshawb fawb tsuas yog kawm txog cov txiaj ntsig ntawm berberine ntawm cov qog nqaij hlav qog noj ntshav hauv chav kuaj thiab tsis nyob hauv tib neeg.
Raws li qee qhov kev tshawb fawb luam tawm xyoo 2020, yog tias berberine tuaj yeem pab kho mob qog noj ntshav, o, ntshav qab zib thiab lwm yam kab mob, nws yuav yog vim nws cov txiaj ntsig zoo rau lub plab microbiome. Cov kws tshawb fawb tau pom qhov sib txuas ntawm lub plab microbiome (cov kab mob hauv cov hnyuv) thiab cov mob no.
Berberine muaj cov tshuaj tua kab mob thiab tshem tawm cov kab mob phem los ntawm cov hnyuv, yog li txhawb kev loj hlob ntawm cov kab mob noj qab haus huv.
Thaum cov kev tshawb fawb hauv tib neeg thiab nas qhia tias qhov no yuav muaj tseeb, cov kws tshawb fawb ceeb toom tias yuav tsum muaj kev tshawb fawb ntxiv kom paub meej tias berberine cuam tshuam rau tib neeg li cas thiab seb nws puas muaj kev nyab xeeb siv.
Lub koom haum American Association of Naturopathic Physicians (AANP) hais tias cov tshuaj berberine muaj nyob rau hauv daim ntawv ntxiv lossis tshuaj ntsiav.
Lawv ntxiv tias ntau cov kev tshawb fawb pom zoo kom noj 900-1500 mg ib hnub, tab sis feem ntau cov neeg noj 500 mg peb zaug ib hnub. Txawm li cas los xij, AANP hais kom tib neeg mus ntsib kws kho mob ua ntej noj berberine los xyuas seb nws puas muaj kev nyab xeeb rau kev siv thiab ntawm qhov koob tshuaj twg nws tuaj yeem noj.
Yog tias tus kws kho mob pom zoo tias berberine muaj kev nyab xeeb rau kev siv, tib neeg yuav tsum kuaj xyuas cov khoom lag luam rau cov ntawv pov thawj thib peb, xws li National Science Foundation (NSF) lossis NSF International, hais tias AANP.
Cov kws sau ntawv ntawm kev tshawb fawb 2018 pom tias cov ntsiab lus ntawm cov tshuaj berberine sib txawv sib txawv, uas tuaj yeem ua rau tsis meej pem txog kev nyab xeeb thiab ntau npaum li cas. Lawv tsis pom tias cov nqi siab dua yuav tsum muaj kev cuam tshuam cov khoom zoo dua.
US Food and Drug Administration (FDA) tsis tswj cov khoom noj khoom haus. Tsis muaj kev lees paub tias cov tshuaj ntxiv muaj kev nyab xeeb lossis siv tau zoo, thiab nws tsis yog ib txwm muaj peev xwm txheeb xyuas qhov zoo ntawm cov khoom.
Cov kws tshawb fawb hais tias berberine thiab metformin sib koom ntau yam ntxwv thiab ob qho tib si yuav muaj txiaj ntsig zoo hauv kev kho mob ntshav qab zib hom 2.
Txawm li cas los xij, yog tias tus kws kho mob sau tshuaj metformin rau ib tus neeg, lawv yuav tsum tsis txhob xav txog berberine ua lwm txoj hauv kev yam tsis tau tham nrog lawv tus kws kho mob thawj zaug.
Cov kws kho mob yuav sau cov koob tshuaj kom raug ntawm metformin rau ib tus neeg raws li kev tshawb fawb soj ntsuam. Nws tsis yooj yim sua kom paub tias cov tshuaj ntxiv zoo npaum li cas rau cov nyiaj no.
Berberine tuaj yeem cuam tshuam nrog metformin thiab cuam tshuam rau koj cov ntshav qab zib, ua rau nws nyuaj rau tswj. Hauv ib txoj kev tshawb fawb, noj berberine thiab metformin ua ke txo cov teebmeem ntawm metformin los ntawm 25%.
Berberine tej zaum yuav yog ib qho kev xaiv tsim nyog rau metformin rau kev tswj ntshav qab zib, tab sis xav tau kev tshawb fawb ntxiv.
Lub National Center for Complementary and Integrative Health (NCCIH) hais tias goldenrod, uas muaj berberine, tsis zoo li yuav ua rau muaj kev phiv loj heev nyob rau lub sij hawm luv luv yog tias cov neeg laus noj nws qhov ncauj. Txawm li cas los xij, tsis muaj cov ntaub ntawv txaus los qhia tias nws muaj kev nyab xeeb rau kev siv mus ntev.
Hauv kev tshawb fawb tsiaj, cov kws tshawb fawb tau sau tseg cov teebmeem hauv qab no nyob ntawm hom tsiaj, tus nqi thiab lub sijhawm ntawm kev tswj hwm:
Nws yog ib qho tseem ceeb uas yuav tau tham nrog koj tus kws kho mob ua ntej noj berberine lossis lwm yam tshuaj ntxiv vim lawv yuav tsis muaj kev nyab xeeb thiab yuav tsis haum rau txhua tus. Txhua tus neeg uas muaj kev tsis haum tshuaj rau txhua yam tshuaj ntsuab yuav tsum tsis txhob siv tam sim ntawd.