Mob qog noj ntshav hauv lub ntsws yog hom mob qog noj ntshav thib ob uas neeg feem ntau ntsib tshaj plaws hauv ntiaj teb. Xyoo 2020, yuav muaj ntau dua 2.2 lab tus tib neeg thoob ntiaj teb raug kuaj pom tias muaj mob qog noj ntshav hauv lub ntsws thawj zaug. Hauv tib lub xyoo ntawd, muaj li ntawm 1.8 lab tus tib neeg thoob ntiaj teb tau tuag vim mob qog noj ntshav hauv lub ntsws.
Txawm hais tias tam sim no tsis muaj kev kho mob qog noj ntshav hauv lub ntsws, cov kws tshawb fawb tab tom ua haujlwm rau cov kev xaiv kho mob. Ib txhia ntawm cov kws tshawb fawb no ua haujlwm ntawm University of Technology Sydney (UTS), qhov chaw uas kev tshawb fawb tshiab tau qhia tias cov nroj tsuag ntuj hu ua berberine tuaj yeem tiv thaiv kev loj hlob ntawm cov hlwb qog noj ntshav hauv chav kuaj mob.
Berberine yog ib hom tshuaj uas muaj nyob hauv cov nroj tsuag uas tau siv rau hauv kev kho mob Suav teb tau ntau txhiab xyoo. Nws pom muaj nyob rau hauv ntau yam nroj tsuag, suav nrog barberry, goldenseal, Oregon grape, thiab turmeric ntoo.

(Peb cov khoom yogBerberine Extract, zoo siab txais tos rau kev nug.)

Xyoo ntawm kev tshawb fawb tau qhia tias berberine muaj txiaj ntsig zoo rau kev pab cov neeg uas muaj ntshav qab zib hom 2 tswj lawv cov ntshav qab zib thiab tej zaum yuav pab kho cov kab mob metabolic syndrome.
Cov kws tshawb nrhiav kuj pom tias berberine tuaj yeem siv los kho ntau yam mob qog noj ntshav, suav nrog mob qog noj ntshav ntawm zes qe menyuam, mob plab, thiab mob qog noj ntshav ntawm lub mis.
Raws li Dr. Kamal Dua, Tus Kws Qhia Ntawv Qib Siab thiab Tus Kws Tshawb Fawb Qib Siab hauv Tsev Muag Tshuaj ntawm Australian Research Center for Complementary and Integrative Medicine (ARCCIM), University of Technology Sydney (UTS) School of Medicine thiab tus thawj coj ntawm txoj kev tshawb fawb no, Berberine inhibits ob txoj hauv kev tseem ceeb hauv kev loj hlob ntawm mob qog noj ntshav - Proliferation thiab cell migration.
"Hauv kev siv tshuab, qhov no tuaj yeem ua tiav los ntawm kev txwv tsis pub cov noob caj noob ces tseem ceeb xws li P53, PTEN thiab KRT18 thiab cov protein xws li AXL, CA9, ENO2, HER1, HER2, HER3, PRGN, PDGF-AA, DKK1, CTSB, CTSD, BCLX, CSF1. thiab CAPG uas cuam tshuam nrog kev loj hlob thiab kev tsiv teb tsaws chaw ntawm cov hlwb qog noj ntshav," nws piav qhia.
Hauv kev tshawb fawb tam sim no, pab pawg tshawb fawb suav nrog Dr. Dua, Dr. Keshav Raj Paudel, Xibfwb Philip M. Hansbrough thiab Dr. Bikash Manandhar ntawm UTS, nrog rau cov neeg ua haujlwm los ntawm Malaysian International Medical University thiab Al Qasim University hauv Saudi Arabia, tau kawm txog yuav ua li cas berberine siv tau los kho mob qog noj ntshav ntsws.
"Kev siv tshuaj berberine hauv kev kho mob muaj tsawg vim nws tsis yaj tau zoo thiab tsis muaj txiaj ntsig," piav qhia Dr. Dua rau MNT. "Lub hom phiaj tseem ceeb ntawm txoj kev tshawb fawb no yog los txhim kho cov yam ntxwv ntawm berberine los ntawm kev hloov berberine mus ua cov khoom siv lead ua kua thiab los tshawb nrhiav nws cov peev xwm tiv thaiv kab mob qog noj ntshav hauv vitro ntawm cov hlwb alveolar epithelial basal ntawm tib neeg adenocarcinoma A549."
Cov pab pawg tshawb fawb tau tsim ib lub tshuab xa tshuaj zoo heev uas muab cov berberine ntim rau hauv cov pob me me uas yaj tau thiab lwj tau. Cov nanoparticles siv lead ua kua no tau siv los kho cov hlwb mob qog noj ntshav hauv lub ntsws hauv vitro hauv chav kuaj mob.
Thaum kawg ntawm txoj kev tshawb fawb, pab neeg pom tias berberine tau pab thaiv kev tsim cov tshuaj reactive oxygen, cov tshuaj lom neeg uas tsim los ntawm qee lub hlwb los teb rau cov kab mob nkag thiab lwm yam kev ntxhov siab uas tuaj yeem ua rau cov hlwb puas tsuaj.
Ntxiv rau, berberine pab tswj cov noob caj noob ces uas cuam tshuam nrog kev ntxhov siab oxidative thiab o, thiab pab txo cov cell laus ua ntej lub sijhawm.
"Peb tau ua pov thawj tias, siv txoj hauv kev nanotechnological, cov khoom ntawm cov tshuaj no tuaj yeem txhim kho kom daws tau ntau yam teeb meem ntsig txog kev yaj, kev nqus ntawm tes, thiab kev kho mob zoo," piav qhia Dr. Dua. Lub Peev Xwm Tiv Thaiv Kab Mob Cancer Peb cov kua siv lead ua kua berberine nanoparticles tau qhia tib yam kev ua haujlwm ntawm tsib zaug ntawm cov koob tshuaj piv rau cov ntaub ntawv luam tawm, qhia meej txog cov txiaj ntsig ntawm cov tshuaj nanodrugs.
Yuav kom sim tau cov txiaj ntsig no ntxiv, Dr. Dua tau hais tias nws npaj yuav siv lub platform tshawb fawb tshiab los ua kev tshawb fawb tob tob siv cov qauv tsiaj ua ntej kuaj mob qog noj ntshav hauv lub ntsws.
"Kev tshawb fawb ntxiv txog pharmacokinetic thiab anticancer ntawm berberine nanodrugs hauv cov qauv tsiaj hauv vivo yuav qhia tau lawv cov txiaj ntsig zoo hauv kev kho mob qog noj ntshav thiab hloov lawv mus rau hauv cov tshuaj kho mob," nws piav qhia.
"Thaum peb tau lees paub qhov muaj peev xwm tiv thaiv kab mob qog noj ntshav ntawm berberine nanodrugs hauv cov qauv tsiaj ua ntej kev kho mob, kauj ruam tom ntej yuav yog txav mus rau kev sim tshuaj, uas peb twb tau sib tham nrog ntau lub tuam txhab hauv Sydney," Dr. Dua hais.
Ntxiv mus, Dr. Dua tau hais tias lub peev xwm ntawm berberine los tiv thaiv kev rov tshwm sim ntawm mob qog noj ntshav hauv lub ntsws yuav tsum tau lees paub: "Txawm hais tias peb tseem tsis tau tshawb nrhiav qhov no, peb npaj yuav kawm nws hauv kev tshawb fawb yav tom ntej, thiab peb kuj ntseeg tias berberine nanoforms yuav qhia txog kev ua haujlwm zoo. ".
Dr. Osita Onuga, kws phais mob hauv siab thiab tus pab xibfwb qhia txog kev phais mob hauv siab ntawm St. John Cancer Institute ntawm Providence St. John Medical Center hauv Santa Monica, California, tau hais rau MNT tias thaum cov kws tshawb fawb pom cov cib fim tshiab los kho thiab tiv thaiv kab mob qog noj ntshav, yeej ib txwm muaj kev cia siab:
"Berberine yog ib feem ntawm cov tshuaj sab hnub tuaj, yog li peb tsis siv nws hauv cov tshuaj sab hnub poob. Kuv xav tias nws nthuav vim peb tab tom saib qhov peb paub tias muaj qee qhov txiaj ntsig rau cov khoom siv tshuaj sab hnub tuaj, thiab muab tso rau hauv kev tshawb fawb los pab txhais qhov ntawd rau hauv cov tshuaj sab hnub poob."
"Nws yeej ib txwm muaj kev cia siab, tab sis nws nyob hauv chav kuaj, thiab ntau yam uas peb pom hauv chav kuaj tsis tas yuav ua rau cov neeg mob raug kho," Onuga hais ntxiv. "Kuv xav tias qhov tom ntej no yuav tsum ua yog ua qee qhov kev sim tshuaj rau cov neeg mob thiab xam seb yuav siv tshuaj ntau npaum li cas."
Muaj ib txhia neeg uas muaj cov tsos mob me me ntawm mob qog noj ntshav ntsws thaum pib mob. Nyeem ntxiv kom paub ntau ntxiv, suav nrog thaum twg yuav tsum mus ntsib kws kho mob.
Mob qog noj ntshav hauv lub ntsws tshwm sim ntawm ntau tus nqi sib txawv rau cov poj niam thiab cov txiv neej, tab sis cov tsos mob thiab cov yam ntxwv uas ua rau muaj kev pheej hmoo zoo ib yam. Ntawm no peb piav qhia txog tej zaum yuav muaj los ntawm noob caj noob ces thiab cov tshuaj hormones ...
Peb yog cov chaw tsim tshuaj ntsuab extract hmoov, txais tos xa koj cov lus nug txog peb cov khoom thiab peb muaj tus npoj yaig uas muaj lub luag haujlwm los daws koj cov teeb meem txog kev muag khoom ua ntej thiab tom qab muag. Tiv tauj peb txhua lub sijhawm !!!